anaxirone

Definition / meaning of anaxirone

A synthetic triepoxide alkylating agent with potential antineoplastic activity. Anaxirone alkylates DNA via actual or derived epoxide groups, resulting in inhibition of DNA synthesis. This agent has been shown to exhibit a broad spectrum of antineoplastic activity against experimental tumors, including those resistant to other alkylating agents.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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