monoclonal antibody CC49-delta CH2

Definition / meaning of monoclonal antibody CC49-delta CH2

A humanized CH2 domain-deleted second-generation monoclonal antibody based on the antibody B72.3 that is directed against tumor-associated glycoprotein 72 (TAG72). TAG72 is expressed by gastric, breast, pancreatic, colorectal, and ovarian carcinoma cells.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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