A synthetic analogue of nucleoside uridine lacking a ring nitrogen in the 3-position. 3-deazauridine inhibits cytidine synthase, thereby reducing intracellular … [Read more...]
Drug Dictionary
Browse and search our online medical database for definitions, meanings and information on medical and prescription drugs. Drug dictionary, drug glossary, drug terminology.
3,4-diaminopyridine
An organic compound derived from pyridine with potassium channel inhibition activity. 3,4-diaminopyridine inhibits potassium channel efflux, increasing the … [Read more...]
3,4-methylenedioxymethamphetamine
A ring-substituted amphetamine derivative, structurally related to the hallucinogen mescaline, with entactogenic, neurotoxic, and motor-stimulatory activities. … [Read more...]
3′-aminomethyl nicotine-P. aeruginosa r-exoprotein A conjugate vaccine
A hapten-carrier immunoconjugate composed of the hapten trans-3'-aminomethyl nicotine conjugated to a recombinant P. aeruginosa exoprotein A, rendered nontoxic … [Read more...]
3′-C-ethynylcytidine
A synthetic cytidine nucleoside containing a covalently bound ethynyl group with potential antineoplastic and radiosensitizing activities. 3'-C-ethynylcytidine … [Read more...]
3′-deoxy-3′-[18F]fluorothymidine
A radioconjugate consisting of a thymidine analogue radiolabeled with fluorine F 18, a positron emitting isotope. Phosphorylated by S-phase-specific thymidine … [Read more...]
4-hydroxytamoxifen
A tamoxifen metabolite with both estrogenic and anti-estrogenic effects. 4-hydroxytamoxifen has a higher affinity for the estrogen receptor than tamoxifen, and … [Read more...]
4-nitroestrone 3-methyl ether
A synthetic derivative of estradiol. 4-nitroestrone 3-methyl ether inhibits estrogen sulfotransferase (EST), a progesterone-induced secretory endometrial enzyme … [Read more...]
4′-iodo-4′-deoxydoxorubicin
An iodinated doxorubicin analogue with antiamyloid activity. 4'-Iodo-4'-deoxydoxorubicin (IDOX) binds with high affinity to five types of natural amyloid … [Read more...]
5-[18F]fluorouracil
The fluorine-18 (18F)-radiolabeled pyrimidine analog 5-fluorouracil (5-FU) with positron-emitting activity. Upon administration, 5-[18F]fluorouracil … [Read more...]