A fluorinated pyrimidine analogue antimetabolite with potential antineoplastic activity. As a prodrug, 5-fluoro-2-deoxycytidine is converted by intracellular … [Read more...]
Drug Dictionary
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5-hydroxytryptophan
An aromatic amino acid with antidepressant activity. In vivo, 5-hydroxytryptophan (5-HTP) is converted into 5-hydroxytryptamine (5-HT or serotonin) as well as … [Read more...]
5,10-methylenetetrahydrofolate
A folate-based biomodulator with potential antineoplastic activity. 5,10-methylenetetrahydrofolate (MTHF) stabilizes the covalent binding of the fluorouracil … [Read more...]
50% oxygen / 50% nitrous oxide premix
An equimolar gas mixture of oxygen (O2) and nitrous oxide (N2O) with potential analgesic activity. Upon inhalation, 50% oxygen/50% nitrous oxide premix produces … [Read more...]
6-azauridine
A synthetic triazine analogue of uridine with antimetabolite activity. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted … [Read more...]
7-cyanoquinocarcinol
A semisynthetic analogue of the Streptomyces melanovinaceus-derived tetracyclic antitumor antibiotic quinocarmycin with potential antineoplastic activity. … [Read more...]
7-hydroxystaurosporine
A synthetic derivative of staurosporine with antineoplastic activity. 7-hydroxystaurosporine inhibits many phosphokinases, including the serine/threonine kinase … [Read more...]
8-hydroxyquinoline sulfate ointment
An ointment formulation containing the sulfate salt of 8-hydroxyquinoline in a petrolatum and lanolin base with skin-protecting activity. Upon topical … [Read more...]
851B gel
A topical gel containing a peptide derived from the human papillomavirus (HPV). Application of 851B gel may stimulate the host immune system to trigger a … [Read more...]
852A
A synthetic imidazoquinoline Toll-like receptor 7 (TLR7) agonist with immunostimulating and potential antitumor activities. TLR7 agonist 852A binds to and … [Read more...]