tegafur-uracil

Definition / meaning of tegafur-uracil

A substance being studied in the treatment of some types of cancer. It is a combination of tegafur and uracil. The tegafur is taken up by the cancer cells and breaks down into 5-FU, a substance that kills tumor cells. The uracil causes higher amounts of 5-FU to stay inside the cells and kill them. Tegafur-uracil is a type of antimetabolite. Also called Ftorafur, UFT, and Uftoral.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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