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ISIS 3521

A synthetic phosphorothioate oligodeoxynucleotide. As an antisense molecule, ISIS 3521 hybridizes to the 3-untranslated region of the human protein kinase C … [Read more...]

ISIS 5132

A synthetic, 20-base antisense oligodeoxynucleotide that hybridizes to c-raf kinase messenger RNA. ISIS 5132 has been shown to specifically suppress Raf-1 … [Read more...]

islet cell

A pancreatic cell that produces hormones (e.g., insulin and glucagon) that are secreted into the bloodstream. These hormones help control the level of glucose … [Read more...]

islet cell carcinoma

A rare cancer that forms in the islets of Langerhans cells (a type of cell found in the pancreas). Also called pancreatic endocrine cancer. … [Read more...]

islet cell tumor

A mass of abnormal cells that forms in the endocrine (hormone-producing) tissues of the pancreas. Islet cell tumors may be benign (not cancer) or malignant … [Read more...]

islet of Langerhans cell

A pancreatic cell that produces hormones (e.g., insulin and glucagon) that are secreted into the bloodstream. These hormones help control the level of glucose … [Read more...]

isoflavone

An estrogen-like substance made by some plants, including the soy plant. Soy isoflavones are being studied in the prevention of cancer, hot flashes that occur … [Read more...]

isointense

Having the same intensity as another object. Used to describe the results of imaging tests, such as x-rays, MRIs, or CT scans. … [Read more...]

isolated hepatic perfusion

A procedure in which a catheter is placed into the artery that provides blood to the liver. A second catheter is placed into the vein that takes blood away from … [Read more...]

isolated limb infusion

A procedure used to deliver anticancer drugs directly to an arm or leg but not to the rest of the body. The flow of blood to and from the limb is temporarily … [Read more...]