The highest dose of a drug or treatment that does not cause unacceptable side effects. The MTD is determined in clinical trials by testing increasing doses on … [Read more...]
M
mTOR
A protein that helps control several cell functions, including cell division and survival, and binds to rapamycin and other drugs. mTOR may be more active in … [Read more...]
mTOR kinase inhibitor AZD2014
An orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. mTOR kinase inhibitor AZD2014 inhibits the … [Read more...]
mTOR kinase inhibitor AZD8055
An inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. mTOR kinase inhibitor AZD8055 inhibits the serine/threonine … [Read more...]
mTOR kinase inhibitor OSI-027
An orally bioavailable mammalian target of rapamycin (mTOR) kinase inhibitor with potential antineoplastic activity. mTOR kinase inhibitor OSI-027 binds to and … [Read more...]
MTX
A drug used to treat some types of cancer, rheumatoid arthritis, and severe skin conditions, such as psoriasis. MTX stops cells from making DNA and may kill … [Read more...]
MUC-1
A substance found on certain epithelial cells (cells that cover organs, glands, and other body surfaces) and on breast cells involved in making milk. It is also … [Read more...]
MUC-1 antigen
MUC-1 antigen is a mammary-type apomucin, a high molecular weight transmembrane glycoprotein, of which the extracellular domain is formed by a repeating 20 … [Read more...]
MUC-1 peptide vaccine
A cancer vaccine comprised of a synthetic peptide derived from the mucin 1 (MUC-1) antigen with potential antineoplastic activity. Upon administration, MUC-1 … [Read more...]
MUC1 peptide-poly-ICLC adjuvant vaccine
A vaccine preparation containing mucus 1 (MUC1) peptide and the adjuvant poly-ICLC with potential immunostimulatory and antineoplastic activities. Upon … [Read more...]