autologous EBV-transformed B lymphoblastoid-tumor fusion cell vaccine

Definition / meaning of autologous EBV-transformed B lymphoblastoid-tumor fusion cell vaccine

A cell-based vaccine composed of autologous tumor cells fused with Epstein-Barr virus-transformed B-lymphoblastoid cells. Upon administration, this vaccine may stimulate a cytotoxic T cell response against tumor cells, resulting in tumor cell lysis.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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