baclofen

Definition / meaning of baclofen

A synthetic chlorophenyl-butanoic acid derivative with muscle relaxant activity. Baclofen acts as a gamma-aminobutyric acid (GABA) agonist specific for GABA-B receptors in the central nervous system (CNS). At spinal and supraspinal sites, this agent reduces excitatory transmission.

Listed under:

Find More About 'baclofen'

Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

Leave a Comment