clindamycin / hydrocortisone lotion

Definition / meaning of clindamycin / hydrocortisone lotion

A topical lotion, containing clindamycin and hydrocortisone, with antibacterial and anti-inflammatory activities. Clindamycin, a lincomycin antibiotic, binds to the 50S subunit of the bacterial ribosome, thereby inhibiting bacterial protein synthesis. As a glucocorticoid agonist, hydrocortisone promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppression of immune and inflammatory responses.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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