death receptor 4

Definition / meaning of death receptor 4

A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer cells. An increase in the amount or activity of death receptor 4 on cancer cells may kill more cells. Also called DR4, TRAIL receptor 1, TRAIL-R1, and tumor necrosis factor receptor superfamily member 10A.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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