HGS-ETR2

Definition / meaning of HGS-ETR2

A substance being studied in the treatment of some types of cancer. It binds to a protein called TRAIL-R2 on the surface of some tumor cells, which may kill the tumor cells. HGS-ETR2 is a type of monoclonal antibody. Also called anti-TRAIL R2 mAb HGS-ETR2 and lexatumumab.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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