HMG-CoA reductase inhibitor

Definition / meaning of HMG-CoA reductase inhibitor

A substance that blocks an enzyme needed by the body to make cholesterol and lowers the amount of cholesterol in the blood. HMG-CoA reductase inhibitor drugs are called statins. Also called hydroxymethylglutaryl-coenzyme A reductase inhibitor.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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