humanized monoclonal antibody

Definition / meaning of humanized monoclonal antibody

A type of antibody made in the laboratory by combining a human antibody with a small part of a mouse or rat monoclonal antibody. The mouse or rat part of the antibody binds to the target antigen, and the human part makes it less likely to be destroyed by the body’s immune system.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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