indium In 111 monoclonal antibody BrE-3

Definition / meaning of indium In 111 monoclonal antibody BrE-3

A humanized monoclonal antibody conjugated to the imaging radioisotope (indium-111). This radioimmunoconjugate binds to the breast epithelial mucin antigen, which is found primarily on breast cancer cells, permitting radioimmmuno-localization of mucin-positive tumor cells and an estimate of radiation dosimetry prior to administration of cytotoxic radiotherapy.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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