iodine I 131 tositumomab

Definition / meaning of iodine I 131 tositumomab

A monoclonal antibody directed against the CD20 protein expressed on the surface of B-lymphocytes and radiolabeled with the radioisotope iodine I 131 with potential antineoplastic activity. Iodine I 131 tositumomab binds to and selectively delivers cyctotoxic radiation to CD20-expressing B-lymphocytes, thereby minimizing systemic radiotoxicity.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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