itraconazole

Definition / meaning of itraconazole

A synthetic triazole agent with antimycotic properties. Formulated for both topical and systemic use, itraconazole preferentially inhibits fugal cytochrome P450 enzymes, resulting in a decrease in fungal ergosterol synthesis. Because of its low toxicity profile, this agent can be used for long-term maintenance treatment of chronic fungal infections.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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