maytansinoid DM4-conjugated humanized monoclonal antibody huC242

Definition / meaning of maytansinoid DM4-conjugated humanized monoclonal antibody huC242

A substance being studied in the treatment of some types of cancer. It is made by linking the monoclonal antibody huC242 to a toxic substance called maytansinoid DM4. The monoclonal antibody binds to the surfaces of cancer cells and the maytansinoid DM4 enters the cells and blocks their growth. It is a type of immunotoxin. Also called huC242-DM4.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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