monoclonal antibody 105AD7 anti-idiotype vaccine

Definition / meaning of monoclonal antibody 105AD7 anti-idiotype vaccine

A cancer vaccine consisting of a humanized monoclonal antibody that mimics a tumor-associated antigen 791Tgp72 (also known as CD55). Vaccination with this agent may stimulate a host cytotoxic T-cell response against tumor cells expressing CD55, resulting in tumor cell lysis.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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