pentamethylmelamine

Definition / meaning of pentamethylmelamine

A principal metabolite of hexamethylmelamine with antineoplastic activity. Pentamethylmelamine alkylates DNA and other macromolecules and forms DNA intrastrand and DNA-protein crosslinks, thereby preventing DNA replication.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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