phase II detoxification

Definition / meaning of phase II detoxification

A process in which the liver uses one of two major enzyme pathways to change a toxic substance, such as an anticancer drug, into a less toxic substance that is easier for the body to excrete. In phase II detoxification, liver cells add a substance (such as cysteine, glycine, or a sulfur molecule) to a toxic chemical or drug, to make it less harmful.

Listed under:

Find More About 'phase II detoxification'

Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

Leave a Comment