yttrium Y 90 monoclonal antibody BrE-3

Definition / meaning of yttrium Y 90 monoclonal antibody BrE-3

A radioimmunotherapeutic agent consisting of a monoclonal antibody (BrE-3) directed against the tumor-associated antigen epithelial glycoprotein mucin chelated to the radioisotope yttrium-90. Yttrium Y 90 monoclonal antibody BrE-3 binds to tumor cells expressing epithelial glycoprotein mucin, selectively delivering a cytotoxic dose of beta radiation.

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Source(s):

The Web site of the National Cancer Institute (http://www.cancer.gov/)

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